United States travel giant Expedia completed a $703 million takeover of Wotif in November and since then it has been reviewing its plans for the Australian company.
It is understood the job losses over the coming weeks will target its Asian operations and its local technology division in particular. In Asia, Wotif has offices in China, Indonesia, Malaysia, Singapore, Thailand and Vietnam.
As of September, Wotif employed 620 people, including 170 technology staff in Sydney and Bangkok. A spokesman for Expedia declined to say how many employees would be leaving the business.